THE SMART TRICK OF PKRRATING THAT NOBODY IS DISCUSSING

The activated enzyme then phosphorylates its main substrate, the translational initiation factor eIF2α. The resulting translational arrest blocks viral replication. PKR belongs into a conserved spouse and children of four protein kinases (PKR, PERK, GCN2, HRI) that every one phosphorylate eIF2α in reaction to unique stimuli12, triggering the buil